Prescription Toujeo^® is a long-acting insulin used to control blood sugar in adults with diabetes mellitus.

• Toujeo^® contains 3 times as much insulin in 1 mL as standard insulin (100 Units/mL)
• Toujeo^® is not for use to treat diabetic ketoacidosis
• Toujeo^® should not be used in children

Do not take Toujeo^® during episodes of low blood sugar or if you are allergic to insulin or any of the inactive ingredients in Toujeo^®.

Do not share insulin pens even if the needle has been changed. Do NOT reuse needles.

Before starting Toujeo^®, tell your doctor about all your medical conditions, including:

• If you have liver or kidney problems
• If you are pregnant or planning to become pregnant
• If you are breast-feeding or planning to breast-feed

Heart failure can occur if you are taking insulin together with certain medicines called TZDs (thiazolidinediones), even if you have never had heart failure or other heart problems. If you already have heart failure, it may get worse while you take TZDs with Toujeo^®. Tell your doctor if you have any new or worsening symptoms of heart failure, including:

• Shortness of breath
• Swelling of your ankles or feet
• Sudden weight gain

Your treatment with TZDs and Toujeo^® may need to be changed or stopped by your healthcare provider if you have new or worsening heart failure.

Tell your doctor about all the medications you take, including over-the-counter medicines, vitamins, and supplements, including herbal supplements.

Toujeo^® should be taken once a day at the same time each day to lower blood glucose. You must test your blood sugar levels daily while using any insulin, including Toujeo^®. Do not make any changes to your dose or type of insulin without talking to your healthcare provider. You should always verify that you have the correct insulin before each injection. Your dose for Toujeo^® may be different from other insulins you have taken. Any change of insulin should be made cautiously and only under medical supervision.

Do NOT dilute or mix Toujeo^® with any other insulin or solution. It will not work as intended and you may lose blood sugar control, which could be serious. Toujeo^® must only be used if the solution is clear and colorless with no particles visible.

While using Toujeo^®, do not drive or operate heavy machinery until you know how Toujeo^® affects you. You should not drink alcohol or use other medicines that contain alcohol.

The most common side effect of any insulin, including Toujeo^®, is low blood sugar (hypoglycemia), which may be serious and can be life-threatening. Severe hypoglycemia may cause harm to your heart or brain. Symptoms of serious low blood sugar may include shaking, sweating, fast heartbeat, and blurred vision.

Toujeo^® may cause serious side effects that can lead to death, such as severe allergic reactions that affect the whole body. Get medical help right away if you have:

• A rash over your whole body
• Trouble breathing
• Shortness of breath
• Fast heartbeat
• Swelling of your face, tongue, or throat
• Sweating
• Extreme drowsiness, dizziness, or confusion

Toujeo^® may have additional side effects. Other possible side effects may include swelling, weight gain, and low potassium.

Injection site reactions are also possible and may include change in fat tissue at the injection site, skin thickening, redness, swelling, and itching.

Toujeo^® SoloStar^® is a disposable prefilled insulin pen. Please talk to your healthcare provider about proper injection technique and follow instructions in the Instruction Leaflet that accompanies the pen.

Please click link below for Full Prescribing Information for Toujeo^®.

Prescription Toujeo^® is a long-acting insulin used to control blood sugar in adults with diabetes mellitus.

• Toujeo^® contains 3 times as much insulin in 1 mL as standard insulin (100 Units/mL)
• Toujeo^® is not for use to treat diabetic ketoacidosis
• Toujeo^® should not be used in children

Do not take Toujeo^® during episodes of low blood sugar or if you are allergic to insulin or any of the inactive ingredients in Toujeo^®.

Do not share insulin pens even if the needle has been changed. Do NOT reuse needles.

Before starting Toujeo^®, tell your doctor about all your medical conditions, including:

• If you have liver or kidney problems
• If you are pregnant or planning to become pregnant
• If you are breast-feeding or planning to breast-feed

Heart failure can occur if you are taking insulin together with certain medicines called TZDs (thiazolidinediones), even if you have never had heart failure or other heart problems. If you already have heart failure, it may get worse while you take TZDs with Toujeo^®. Tell your doctor if you have any new or worsening symptoms of heart failure, including:

• Shortness of breath
• Swelling of your ankles or feet
• Sudden weight gain

Your treatment with TZDs and Toujeo^® may need to be changed or stopped by your healthcare provider if you have new or worsening heart failure.

Tell your doctor about all the medications you take, including over-the-counter medicines, vitamins, and supplements, including herbal supplements.

Toujeo^® should be taken once a day at the same time each day to lower blood glucose. You must test your blood sugar levels daily while using any insulin, including Toujeo^®. Do not make any changes to your dose or type of insulin without talking to your healthcare provider. You should always verify that you have the correct insulin before each injection. Your dose for Toujeo^® may be different from other insulins you have taken. Any change of insulin should be made cautiously and only under medical supervision.

Do NOT dilute or mix Toujeo^® with any other insulin or solution. It will not work as intended and you may lose blood sugar control, which could be serious. Toujeo^® must only be used if the solution is clear and colorless with no particles visible.

While using Toujeo^®, do not drive or operate heavy machinery until you know how Toujeo^® affects you. You should not drink alcohol or use other medicines that contain alcohol.

The most common side effect of any insulin, including Toujeo^®, is low blood sugar (hypoglycemia), which may be serious and can be life-threatening. Severe hypoglycemia may cause harm to your heart or brain. Symptoms of serious low blood sugar may include shaking, sweating, fast heartbeat, and blurred vision.

Toujeo^® may cause serious side effects that can lead to death, such as severe allergic reactions that affect the whole body. Get medical help right away if you have:

• A rash over your whole body
• Trouble breathing
• Shortness of breath
• Fast heartbeat
• Swelling of your face, tongue, or throat
• Sweating
• Extreme drowsiness, dizziness, or confusion

Toujeo^® may have additional side effects. Other possible side effects may include swelling, weight gain, and low potassium.

Injection site reactions are also possible and may include change in fat tissue at the injection site, skin thickening, redness, swelling, and itching.

Toujeo^® SoloStar^® is a disposable prefilled insulin pen. Please talk to your healthcare provider about proper injection technique and follow instructions in the Instruction Leaflet that accompanies the pen.